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Hoodia Gordonii - Side Effects Of This Magic Weight Loss Plant Hoodia Gordonii, a dietary supplement stemming from a rare cactus plant in the tribal region of South Africa, is a highly popular weight loss tool. It has been publicized by reports on the Oprah Winfrey show, ABC News and 60 Minutes. Does Hoodia Really Help to Lose Weight? Hoodia may be a new weight loss phenomenon to those of us outside of Africa, but to the native Bushmen of South Africa, the natural appetite-suppressing abilities of the Hoodia plant, or more specifically the Hoodia Gordonii species, come as nothing new. Hoodia - magic plant for losing weight Hoodia is a succulent plant that closely resembles a cactus and grows exclusively in the South African deserts. Recently this purple-flowered plant has been getting a considerable amount of attention for its beneficial weight loss properties.